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Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using IDE Monoclonal antibody (67106-1-Ig)

    WB analysis using 67106-1-Ig (same clone as 67106-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67106-1-Ig (IDE antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67106-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HeLa cells using IDE Monoclonal antibody (67106-1-Ig)

    WB analysis of HeLa using 67106-1-Ig (same clone as 67106-1-PBS)

    WB result of IDE antibody (67106-1-Ig; 1:10000; incubated at room temperature for 1.5 hours) with sh-Control and sh-IDE transfected HeLa cells. This data was developed using the same antibody clone with 67106-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HeLa cells using IDE Monoclonal antibody (67106-1-Ig)

    WB analysis of HeLa using 67106-1-Ig (same clone as 67106-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 67106-1-Ig (IDE antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67106-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of A375 cells using IDE Monoclonal antibody (67106-1-Ig)

    WB analysis of A375 using 67106-1-Ig (same clone as 67106-1-PBS)

    A375 cells were subjected to SDS PAGE followed by western blot with 67106-1-Ig (IDE antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67106-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HepG2 cells using IDE Monoclonal antibody (67106-1-Ig)

    WB analysis of HepG2 using 67106-1-Ig (same clone as 67106-1-PBS)

    HepG2 cells were subjected to SDS PAGE followed by western blot with 67106-1-Ig (IDE antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67106-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of Jurkat cells using IDE Monoclonal antibody (67106-1-Ig)

    WB analysis of Jurkat using 67106-1-Ig (same clone as 67106-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 67106-1-Ig (IDE antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67106-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HSC-T6 cells using IDE Monoclonal antibody (67106-1-Ig)

    WB analysis of HSC-T6 using 67106-1-Ig (same clone as 67106-1-PBS)

    HSC-T6 cells were subjected to SDS PAGE followed by western blot with 67106-1-Ig (IDE antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67106-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of NIH/3T3 cells using IDE Monoclonal antibody (67106-1-Ig)

    WB analysis of NIH/3T3 using 67106-1-Ig (same clone as 67106-1-PBS)

    NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 67106-1-Ig (IDE antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67106-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of RAW 264.7 cells using IDE Monoclonal antibody (67106-1-Ig)

    WB analysis of RAW 264.7 using 67106-1-Ig (same clone as 67106-1-PBS)

    RAW 264.7 cells were subjected to SDS PAGE followed by western blot with 67106-1-Ig (IDE antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67106-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using IDE Monoclonal antibody (67106-1-Ig)

    WB analysis using 67106-1-Ig (same clone as 67106-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67106-1-Ig (IDE antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67106-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse liver tissue using IDE Monoclonal antibody (67106-1-Ig)

    IHC staining of mouse liver using 67106-1-Ig (same clone as 67106-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 67106-1-Ig (IDE antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67106-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse liver tissue using IDE Monoclonal antibody (67106-1-Ig)

    IHC staining of mouse liver using 67106-1-Ig (same clone as 67106-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 67106-1-Ig (IDE antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67106-1-PBS in a different storage buffer formulation.

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  • Featured Product
  • KD/KO Validated

IDE Monoclonal antibody, PBS Only

IDE Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 67106-1-PBS
Clone No.3E10G1

Host / Isotype

Mouse / IgG2b

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Synonyms

Insulin-degrading enzyme, Insulinase, Insulin protease, EC:3.4.24.56, Abeta-degrading protease

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

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約2万点のプロテインテック製品をコスモバイオ社物流センター（国内）に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。

保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換／補填対応を承ります。詳細はこちらをご覧ください。

Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

67106-1-PBS targets IDE in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Immunogen IDE fusion protein Ag17161 相同性解析による交差性が予測される生物種
Full Name Abeta degrading protease
Calculated molecular weight 1019 aa, 118 kDa
Observed molecular weight 100-120 kDa
GenBank accession numberBC096336
Gene Symbol IDE
Gene ID (NCBI) 3416
RRIDAB_2882410
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP14735
Storage Buffer PBS only , pH 7.3
Storage ConditionsStore at -80°C.

Background Information

IDE(INS-degrading enzyme) belongs to the peptidase M16 family. It is also known as insulysin and is a 110-kD neutral metallopeptidase that can degrade a number of peptides, including INS and beta-amyloid(PMID:9830016). The reduction of IDE expression may be a risk factor for AD, and that IDE may interact with APOE status to affect beta-amyloid metabolism(PMID:12507914). It can exsit as a homodimer and form higher oligomers(PMID:17613531).