IDH1 Recombinant antibody, PBS Only
IDH1 Recombinant Antibody for WB, IHC, FC (Intra), Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, IHC, FC (Intra), Indirect ELISA
Conjugate
Unconjugated
CloneNo.
6L18
Cat no : 81176-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
81176-1-PBS targets IDH1 in WB, IHC, FC (Intra), Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | IDH1 fusion protein Ag19749 相同性解析による交差性が予測される生物種 |
Full Name | isocitrate dehydrogenase 1 (NADP+), soluble |
Calculated molecular weight | 414 aa, 47 kDa |
Observed molecular weight | 46 kDa |
GenBank accession number | BC012846 |
Gene symbol | IDH1 |
Gene ID (NCBI) | 3417 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
IDH1, also named as PICD and IDP, belongs to the isocitrate and isopropylmalate dehydrogenases family. It is a common feature of a major subset of primary human brain cancers. It can form a homodimer(PMID:15173171). IDH1 mutation is always heterozygotic and IDH1 functions as a dimer, theoretically there will be 25% each wild type and mutant homo-dimers and 50% hetero-dimers present in the tumor cells(PMID:21079649 ).