IFN Alpha Polyclonal antibody
IFN Alpha Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human and More (1)
Applications
WB, IHC, IF, ELISA
Conjugate
Unconjugated
Cat no : 18013-1-AP
Synonyms
Validation Data Gallery
Tested Applications
| Positive WB detected in | Recombinant protein |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:6000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 5 publications below |
| IHC | See 5 publications below |
| IF | See 2 publications below |
Product Information
The immunogen of 18013-1-AP is IFN Alpha Fusion Protein expressed in E. coli.
| Tested Reactivity | human |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | IFN Alpha fusion protein Ag12533 相同性解析による交差性が予測される生物種 |
| Full Name | IFNA1 |
| Calculated molecular weight | 189 aa, 22 kDa |
| GenBank accession number | BC074928 |
| Gene symbol | IFN alpha1 |
| Gene ID (NCBI) | 3439 |
| RRID | AB_2878481 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
IFNA1 (IFN-alpha) is a member of the Type I IFN (1) family best known for their antiviral activity. It is a key cytokine regulating the activity of B cells, T-helper cells (Th cells), cDCs and natural killer cells (NK cells). IFN-alpha induces B cell maturation into plasma cells and immunoglobulin production. IFN-alpha plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). IFN-alpha was the first cytokine to show clinical benefit in the treatment of certain types of cancer, including melanoma, chronic myelogenous leukemia, and renal cancer.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for IFN Alpha antibody 18013-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
J Immunother Cancer Helicobacter pylori infection disturbs the tumor immune microenvironment and is associated with a discrepant prognosis in gastric de novo diffuse large B-cell lymphoma. | ||
mBio Early enterovirus translation deficits extend viral RNA replication and elicit sustained MDA5-directed innate signaling | ||
Ann Allergy Asthma Immunol Lower viral loads in subjects with rhinovirus-challenged allergy despite reduced innate immunity. | ||
Immunol Lett Acute Effects of TLR3 agonist Poly(I:C) on Bone Marrow Hematopoietic Progenitor Cells in Mice | ||
Dig Liver Dis Innate and adaptive immunity in self-reported nonceliac gluten sensitivity versus celiac disease. | ||
