IHCeasy TP63 Ready-To-Use IHC Kit

TP63 Ready-to-use reagent kit for IHC.

Reactivity

Human, Mouse, Rat

Sample Type

FFPE tissue

Cat no : KHC0086

Synonyms

AIS, B(p51A), B(p51B), CUSP, DNp63, EEC3, KET, LMS, NBP, OFC8, p53CP, p63, RHS, SHFM4, TP53CP, TP63, Tumor protein 63



Product Information

KHC0086 is a ready-to-use IHC kit for staining of TP63. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data.

Product name IHCeasy TP63 Ready-To-Use IHC Kit
Sample type FFPE tissue
Assay type Immunohistochemistry
Primary antibody type Mouse Monoclonal
Secondary antibody type Polymer-HRP-Goat anti-Mouse
Reactivity Human, Mouse, Rat

Kit components

ComponentSizeConcentration
Antigen Retrieval Buffer100 mL50×
Washing Buffer100 mL ×220×
Blocking Buffer5 mLRTU
Primary Antibody5 mLRTU
Secondary Antibody5 mLRTU
Chromogen Component A0.2 mLRTU
Chromogen Component B4 mLRTU
Signal Enhancer5 mLRTU
Counter Staining Reagent5 mLRTU
Mounting Media5 mLRTU
Datasheet1 Copy
Manual1 Copy

Background Information

TP63, also named KET, P63, P73H, P73L and TP73L, belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor.

Properties

Storage Instructions All the reagents are stored at 2-8°C. The kit is stable for 6 months from the date of receipt.
Synonyms AIS, B(p51A), B(p51B), CUSP, DNp63, EEC3, KET, LMS, NBP, OFC8, p53CP, p63, RHS, SHFM4, TP53CP, TP63, Tumor protein 63

Publications

ApplicationTitle
IHC

Nat Commun

UPP1 promotes lung adenocarcinoma progression through the induction of an immunosuppressive microenvironment

Authors - Yin Li