IKBKAP Polyclonal antibody
IKBKAP Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
WB, ELISA
Conjugate
Unconjugated
Cat no : 31705-1-AP
Synonyms
Validation Data Gallery
Tested Applications
| Positive WB detected in | HeLa cells, HepG2 cells, U-251 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:2000-1:12000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
31705-1-AP targets IKBKAP in WB, ELISA applications and shows reactivity with Human samples.
| Tested Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | IKBKAP fusion protein Ag35286 相同性解析による交差性が予測される生物種 |
| Full Name | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
| Calculated molecular weight | 150kDa，1332aa |
| Observed molecular weight | 140-150 kDa |
| GenBank accession number | NM_001318360.1 |
| Gene symbol | IKBKAP |
| Gene ID (NCBI) | 8518 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
IKBKAP, also known as ELP1. It is expected to be located in the cytoplasm and nucleus, which is ubiquitinated in adrenal and ovary tissue. The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. And it exists in homodimer. The molecular weight of IKBKAP is 150 kDa.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for IKBKAP antibody 31705-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
