Anti-Human IL-12RB1/CD212 Rabbit Recombinant Antibody
IL-12RB1/CD212 Recombinant Antibody for FC
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
FC
Conjugate
Unconjugated
CloneNo.
241661H1
Cat no : 98149-1-RR
Synonyms
Validation Data Gallery
Tested Applications
Positive FC detected in | anti-CD3/CD28 treated human PBMCs |
Recommended dilution
Application | Dilution |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
98149-1-RR targets IL-12RB1/CD212 in FC applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Recombinant |
Type | Antibody |
Immunogen | Recombinant Protein 相同性解析による交差性が予測される生物種 |
Full Name | interleukin 12 receptor, beta 1 |
Calculated molecular weight | 662 aa, 73 kDa |
GenBank accession number | BC029121 |
Gene symbol | IL12RB1 |
Gene ID (NCBI) | 3594 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purfication |
Storage Buffer | PBS with 0.09% sodium azide, pH 7.3. |
Storage Conditions | Store at 2 - 8°C. Stable for one year after shipment. |
Background Information
Interleukin-12 receptor subunit beta-1 (IL-12RB1), also named as CD212, is a 662 amino acid protein, which contains 5 fibronectin type-III domains and belongs to the type I cytokine receptor family. IL-12RB1 localizes in the membrane and functions as an interleukin receptor which binds IL-12 with low affinity and is involved in IL-12 transduction. Associated with IL-12RB2 it forms a functional, high affinity receptor for IL-12. It can also associate with IL23R to form the interleukin-23 receptor which functions in IL-23 signal transduction probably through activation of the Jak-Stat signaling cascade.
Protocols
Product Specific Protocols | |
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FC protocol for IL-12RB1/CD212 antibody 98149-1-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |