IL-36RN Polyclonal antibody

IL-36RN Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 13113-1-AP

Synonyms

FIL1, FIL1 delta, FIL1(DELTA), FIL1D, IL 1 delta, IL 1 related protein 3, IL 1F5, IL 1HY1, IL 1L1, IL 1ra homolog 1, IL 1RP3, IL1F5, IL-1F5, IL1HY1, IL1L1, IL1RP3, IL-36Ra, IL-36RN, Interleukin 1 delta, Interleukin 1 family member 5, Interleukin 1 HY1, Interleukin 1 like protein 1


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Tested Applications

Positive IHC detected inhuman skin cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

IHCSee 1 publications below

Product Information

13113-1-AP targets IL-36RN in IHC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen IL-36RN fusion protein Ag3780 相同性解析による交差性が予測される生物種
Full Name interleukin 1 family, member 5 (delta)
Calculated molecular weight 155 aa, 17 kDa
GenBank accession numberBC024747
Gene symbol IL-36RN
Gene ID (NCBI) 26525
RRIDAB_2877917
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

IL36RN is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). It inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling.

Protocols

Product Specific Protocols
IHC protocol for IL-36RN antibody 13113-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIHC

PLoS One

Gene signatures associated with barrier dysfunction and infection in oral lichen planus identified by analysis of transcriptomic data

Authors - Phuc Thi-Duy Vo