IL-7 Monoclonal antibody
IL-7 Monoclonal Antibody for ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
human
Applications
WB, IF, ELISA
Conjugate
Unconjugated
CloneNo.
5D5G7
Cat no : 60206-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 2 publications below |
| IF | See 1 publications below |
Product Information
The immunogen of 60206-1-Ig is IL-7 Fusion Protein expressed in E. coli.
| Tested Reactivity | human |
| Cited Reactivity | human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Affinity | KD=7.40 x 10-10M KOff=7.82 x 10-6M KOn=1.06 x 104M |
| Immunogen | IL-7 fusion protein Ag16314 相同性解析による交差性が予測される生物種 |
| Full Name | interleukin 7 |
| Calculated molecular weight | 20 kDa |
| GenBank accession number | BC047698 |
| Gene symbol | IL-7 |
| Gene ID (NCBI) | 3574 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Interleukin-7 (IL7) is a cytokine mportant for B and T cell development. IL7 plays an active role in the development, survival, maintaining and restoring homeostasis of mature T lymphocytes. It is also a key regulator of the commitment, survival, proliferation and maturation of B cells during development. Furthermore, IL7 can improve the antiviral function and expansion of natural killer (NK) cells and regulate the development and differentiation of dendritic cells. IL7 has also been reported as a regulator of the development of central nervous system and myogenesis and skeletal muscle cell migration.
Publications
| Species | Application | Title |
|---|---|---|
Sci Rep Anti-inflammatory effects of α-MSH through p-CREB expression in sarcoidosis like granuloma model. | ||
Sci Rep Interleukin-7 Contributes to the Invasiveness of Prostate Cancer Cells by Promoting Epithelial-Mesenchymal Transition. | ||
Free Radic Biol Med Oxidative stress-induced IL-15 transtrans-presentation in keratinocytes contributes to CD8+ T cells activation via JAK-STAT pathway in vitiligo. |
