IMP3 Monoclonal antibody, PBS Only
IMP3 Monoclonal Antibody for WB, IHC, IF/ICC, FC (Intra), Indirect ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
mouse, human
Applications
WB, IHC, IF/ICC, FC (Intra), Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1E7D6
Cat no : 66247-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66247-1-PBS targets IMP3 in WB, IHC, IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with mouse, human samples.
Tested Reactivity | mouse, human |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | IMP3 fusion protein Ag23602 相同性解析による交差性が予測される生物種 |
Full Name | IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast) |
Calculated molecular weight | 184 aa, 22 kDa |
Observed molecular weight | 22 kDa |
GenBank accession number | BC020557 |
Gene symbol | IMP3 |
Gene ID (NCBI) | 55272 |
RRID | AB_2881636 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
IMP3 is a member of the insulin-like growth factor (IGF-II) mRNA binding protein (IMP) family that consist of IMP1, IMP2, and IMP3. IMP3 is an oncofetal protein associated with aggressive and advanced tumors and is specifically expressed in malignant tumors but not found in benign tissues [PMID:22497850]. IMP3 forms a ternary complex with IMP4 and MPP10 (MPHOSPH10) that interacts with U3 small nucleolar RNA (snoRNA), which is required for the early cleavage steps in pre-rRNA processing[PMID: 12655004].