INPP5E Monoclonal antibody, PBS Only
INPP5E Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
Human
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2B3D6
Cat no : 68602-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
68602-1-PBS targets INPP5E in WB, Indirect ELISA applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | INPP5E fusion protein Ag11959 相同性解析による交差性が予測される生物種 |
Full Name | inositol polyphosphate-5-phosphatase, 72 kDa |
Calculated molecular weight | 644 aa, 70 kDa |
Observed molecular weight | 72 kDa |
GenBank accession number | BC028032 |
Gene symbol | INPP5E |
Gene ID (NCBI) | 56623 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
INPP5E(72 kDa inositol polyphosphate 5-phosphatase) converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns-P2.In mouse, highest protein expression was in brain, heart, and testis, with lower expression in thymus and lung, and very little expression in kidney, spleen, and liver(PMID:10764818). Defects in INPP5E are the cause of Joubert syndrome type 1 (JBTS1) and mental retardation-truncal obesity-retinal dystrophy-micropenis (MORMS)(PMID:19668215).