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IRF9 Recombinant antibody

IRF9 Uni-rAbTM Recombinant Antibody for WB, ELISA
Cat No. 85160-2-RR
Clone No.242772F12

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

ISGF-3 gamma, IRF-9, IRF 9, Interferon-stimulated gene factor 3 gamma, IFN-alpha-responsive transcription factor subunit

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -


ご購入について

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Positive WB detected inHeLa cells, MCF-7 cells, THP-1 cells, A549 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

85160-2-RR targets IRF9 in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen IRF9 fusion protein Ag5365 相同性解析による交差性が予測される生物種
Full Name IRF 9
Calculated molecular weight 393 aa, 44 kDa
Observed molecular weight 44-48 kDa
GenBank accession numberBC035716
Gene Symbol IRF9
Gene ID (NCBI) 10379
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ00978
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

IRF9 also named ISGF3 is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of IFN stimulated genes, which drive the cell in an antiviral state.

Protocols

Product Specific Protocols
WB protocol for IRF9 antibody 85160-2-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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