CXCR2 Polyclonal antibody
CXCR2 Polyclonal Antibody for IHC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
mouse
Applications
IHC, ELISA
Conjugate
Unconjugated
Cat no : 19538-1-AP
Synonyms
Validation Data Gallery
Tested Applications
| Positive IHC detected in | mouse spleen tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| IHC | See 1 publications below |
Product Information
19538-1-AP targets CXCR2 in IHC, ELISA applications and shows reactivity with mouse samples.
| Tested Reactivity | mouse |
| Cited Reactivity | mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | interleukin 8 receptor, beta |
| Calculated molecular weight | 41 kDa |
| GenBank accession number | NM_009909 |
| Gene symbol | Cxcr2 |
| Gene ID (NCBI) | 12765 |
| RRID | AB_2878587 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Cmkar2, also named as Cxcr2, Gpcr16 and CD182, belongs to the G-protein coupled receptor 1 family. Il8rb is a receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Il8rb binds to IL-8 with high affinity. Il8rb also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. This antibody is specific to mouse Il8rb.
Protocols
| Product Specific Protocols | |
|---|---|
| IHC protocol for CXCR2 antibody 19538-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Adv Sci (Weinh) Tumor Microenvironment Responsive CD8+ T Cells and Myeloid-Derived Suppressor Cells to Trigger CD73 Inhibitor AB680-Based Synergistic Therapy for Pancreatic Cancer |
