Islet 1 Recombinant antibody
Islet 1 Recombinant Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, ELISA
Conjugate
Unconjugated
CloneNo.
240833B2
Cat no : 83784-6-RR
Synonyms
Validation Data Gallery
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Tested Applications
| Positive WB detected in | SH-SY5Y cells, Y79 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
The immunogen of 83784-6-RR is Islet 1 Fusion Protein expressed in E. coli.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Islet 1 fusion protein Ag33541 相同性解析による交差性が予測される生物種 |
| Full Name | ISL LIM homeobox 1 |
| Calculated molecular weight | 39 kDa |
| Observed molecular weight | 39-45 kDa |
| GenBank accession number | BC031213 |
| Gene symbol | Islet 1 |
| Gene ID (NCBI) | 3670 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
ISL1 belongs to the LIM homeodomain transcription factor family that binds to the enhancer region of the INS gene. It plays a pivotal role in cardiogenesis, and lacking ISL1 expression results in growth arrest or displays profound defects in heart development, including atria, ventricle, and the inflow and outflow tracts. Ubiquitinated probably by WWP1 E3 ubiquitin ligase; ubiquitination is followed by protein degradation.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for Islet 1 antibody 83784-6-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
