- Featured Product
- KD/KO Validated
JAK1 Monoclonal antibody, PBS Only
JAK1 Monoclonal Antibody for WB, IHC, ELISA
Host / Isotype
Mouse / IgG2b
Reactivity
human, rat, mouse
Applications
WB, IHC, ELISA
Conjugate
Unconjugated
CloneNo.
3H7A8
Cat no : 66466-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66466-1-PBS targets JAK1 in WB, IHC, ELISA applications and shows reactivity with human, rat, mouse samples.
Tested Reactivity | human, rat, mouse |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | JAK1 fusion protein Ag17940 相同性解析による交差性が予測される生物種 |
Full Name | Janus kinase 1 (a protein tyrosine kinase) |
Calculated molecular weight | 1154 aa, 133 kDa |
Observed molecular weight | 133 kDa |
GenBank accession number | BC132729 |
Gene symbol | JAK1 |
Gene ID (NCBI) | 3716 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS only |
Storage Conditions | Store at -80°C. |
Background Information
Janus kinase 1(JAK1), is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. JAK1 is essential for signaling for certain type I and type II cytokines. JAK1 plays a critical role in initiating responses to multiple major cytokine receptor families. Expression of JAK1 in cancer cells enables individual cells to contract, potentially allowing them to escape their tumor and metastasize to other parts of the body.