Validation Data Gallery
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Tested Applications
| Positive WB detected in | mouse liver tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 3 publications below |
Product Information
19697-1-AP targets Kv1.4-Specific in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | potassium voltage-gated channel, shaker-related subfamily, member 4 |
| Calculated molecular weight | 73 kDa |
| Observed molecular weight | 68-73 kDa |
| GenBank accession number | NM_002233 |
| Gene Symbol | Kv1.4 |
| Gene ID (NCBI) | 3739 |
| RRID | AB_10638919 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P22459 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
KCNA4, also named as KCNA4L, HBK4, HUKII, HK1 and HPCN2, belongs to the potassium channel family and A (Shaker) subfamily. KCN4 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The antibody is specific to KCN4.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for Kv1.4-Specific antibody 19697-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Cell Physiol Biochem MiR-223-3p as a Novel MicroRNA Regulator of Expression of Voltage-Gated K+ Channel Kv4.2 in Acute Myocardial Infarction. | ||
J Cell Sci Nucleoporin 50 mediates Kcna4 transcription to regulate cardiac electrical activity. | ||
J Cell Mol Med Nucleoporin 107 facilitates the nuclear export of Scn5a mRNA to regulate cardiac bioelectricity. |