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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

KCNA6 Polyclonal antibody

KCNA6 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 31900-1-AP

Synonyms

Protein Phosphatase 1, Regulatory Subunit 96, PPP1R96, Potassium voltage-gated channel subfamily A member 6, Kv1.6, Human Brain Potassium Channel-2

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using KCNA6 Polyclonal antibody (31900-1-AP)

    WB analysis using 31900-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 31900-1-AP (KCNA6 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

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Tested Applications

Positive WB detected inDaudi cells, Jurkat cells, Raji cells, TT cells, U2OS cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

31900-1-AP targets KCNA6 in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen KCNA6 fusion protein Ag35654 相同性解析による交差性が予測される生物種
Full Name potassium voltage-gated channel, shaker-related subfamily, member 6
Calculated molecular weight59 kDa，529aa
Observed molecular weight65 kDa
GenBank accession numberNM_002235.3
Gene symbol KCNA6
Gene ID (NCBI) 3742
RRIDAB_3670137
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity Purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

The Shaker-like Kv1 potassium channel family comprises 8 α subunits (Kv1.1-Kv1.8), which are key regulators of neuronal excitability in mammals (PMID: 7842011; 9581771; 22612818). Potassium voltage-gated channel subfamily A member 6 (KCNA6, also known as HBK2, Kv1.6, and PPP1R96) is a multi-pass membrane protein that is mainly expressed in the central and peripheral nervous system (PMID: 12042352; 8872310). The concentration of the Kv1.6 channel in the cell membrane can modulate the kinetic properties of Kv1.6-induced K+ current (PMID: 14575698).

Protocols

Product Specific Protocols
WB protocol for KCNA6 antibody 31900-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols