KCNE4 Polyclonal antibody
KCNE4 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, IF, IHC, ELISA
Conjugate
Unconjugated
Cat no : 18289-1-AP
Synonyms
Validation Data Gallery
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Tested Applications
| Positive WB detected in | L02 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 3 publications below |
| IHC | See 1 publications below |
| IF | See 2 publications below |
Product Information
18289-1-AP targets KCNE4 in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | potassium voltage-gated channel, Isk-related family, member 4 |
| Calculated molecular weight | 18 kDa |
| Observed molecular weight | 25-30 kDa |
| GenBank accession number | NM_080671 |
| Gene symbol | KCNE4 |
| Gene ID (NCBI) | 23704 |
| RRID | AB_2132300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
KCNE4, also named as MIRP3 and MGC2035, is a membrane protein belongs to a family of single transmembrane domain proteins known to have dramatic effect on the gating of certain potassium channels. KCNE4 is expressed strongly in heart, skeletal muscle and kidney. Electrophysiological studies show that human KCNE4 modulates the activation of the KCNQ1 channel.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for KCNE4 antibody 18289-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
J Cell Sci The C-terminal domain of Kv1.3 regulates functional interactions with the KCNE4 subunit. | ||
FASEB J The calmodulin-binding tetraleucine motif of KCNE4 is responsible for association with Kv1.3. |
