Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
19759-1-AP targets KCNT1 in ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | potassium channel, subfamily T, member 1 |
| Calculated molecular weight | 138 kDa |
| GenBank accession number | NM_020822 |
| Gene Symbol | KCNT1 |
| Gene ID (NCBI) | 57582 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q5JUK3 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
KCNT1, also anmed as KIAA1422 and KCa4.1, belongs to the potassium channel family and Calcium-activated subfamily. KCNT1 is outwardly rectifying potassium channel subunit that may co-assemble with other Slo-type channel subunits. It activated by high intracellular sodium or chloride levels. KCNT1 also activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. It may be regulated by calcium in the absence of sodium ions (in vitro).