L3MBTL2 Polyclonal antibody
L3MBTL2 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, ELISA
Conjugate
Unconjugated
Cat no : 24435-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | U2OS cells |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:500-1:2000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
24435-1-AP targets L3MBTL2 in WB, ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | L3MBTL2 fusion protein Ag19571 相同性解析による交差性が予測される生物種 |
Full Name | l(3)mbt-like 2 (Drosophila) |
Calculated molecular weight | 705 aa, 79 kDa |
Observed molecular weight | 95-100 kDa |
GenBank accession number | BC017191 |
Gene symbol | L3MBTL2 |
Gene ID (NCBI) | 83746 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
L3MBTL2 (Lethal (3) malignant brain tumor like 2) is a member of the MBT-domain proteins, which are involved in transcriptional repression and implicated in chromatin compaction. L3MBTL2 was most highly expressed in pachytene spermatocytes within the testis (PMID: 30760872).In addition, mutations in L3MBTL2 are prevalent in various cancers including leukemia, a disease characterized by alterations in multiple DNA repair proteins (PMID: 29581593).
Protocols
Product Specific Protocols | |
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WB protocol for L3MBTL2 antibody 24435-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |