CD107b / LAMP2 Polyclonal antibody

LAMP2 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (2)

Applications

IF, IHC, ELISA

Conjugate

Unconjugated

Cat no : 10397-1-AP

Synonyms

CD107b, LAMP 2, LAMP2, LAMPB, LGP110


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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

10397-1-AP targets LAMP2 in IF, IHC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivity human, rat, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen LAMP2 fusion protein Ag0595 相同性解析による交差性が予測される生物種
Full Name lysosomal-associated membrane protein 2
Calculated molecular weight 45 kDa
GenBank accession numberBC002965
Gene symbol LAMP2
Gene ID (NCBI) 3920
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Lysosomal-associated membrane protein 2 (LAMP2, synonyms: LAMPB, CD107b) is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may plays a role in tumor cell metastasis. It may also functions in the protection, maintenance, and adhesion of the lysosome. Prior to posttranslational modification, LAMP2 is a ~45 kDa polypeptide. Mature, functional LAMP2 is extensively glycosylated with a variety of different N linked and O linked oligosaccharides, with apparent molecular weight ranging from 45-130 kDa.

Publications

SpeciesApplicationTitle
humanIF

Oxid Med Cell Longev

The Inhibition of miR-873 Provides Therapeutic Benefit in a Lipopolysaccharide-Induced Neuroinflammatory Model of Parkinson's Disease.

Authors - Jinhua Wu
human

Cell Death Dis

Dual induction of apoptotic and autophagic cell death by targeting survivin in head neck squamous cell carcinoma.

Authors - L Zhang
humanIF

Acta Neuropathol Commun

Novel antibodies reveal presynaptic localization of C9orf72 protein and reduced protein levels in C9orf72 mutation carriers.

Authors - Petra Frick
mouseIF

Sci Rep

Basal autophagy prevents autoactivation or enhancement of inflammatory signals by targeting monomeric MyD88.

Authors - Takeshi Into
mouse

Biomedicines

IGF-1 as a Potential Therapy for Spinocerebellar Ataxia Type 3.

Authors - Yong-Shiou Lin
mouseIF

Front Pharmacol

Glutamine Availability Regulates the Development of Aging Mediated by mTOR Signaling and Autophagy.

Authors - Jiao Zhou