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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

LINGO1 Polyclonal antibody, PBS Only

LINGO1 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 19097-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of mouse brain tissue using LINGO1 Polyclonal antibody (19097-1-AP)

    WB analysis of mouse brain using 19097-1-AP (same clone as 19097-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 19097-1-AP (LINGO1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19097-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse brain tissue using LINGO1 Polyclonal antibody (19097-1-AP)

    WB analysis of mouse brain using 19097-1-AP (same clone as 19097-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 19097-1-AP (LINGO1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19097-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of rat brain tissue using LINGO1 Polyclonal antibody (19097-1-AP)

    WB analysis of rat brain using 19097-1-AP (same clone as 19097-1-PBS)

    rat brain tissue were subjected to SDS PAGE followed by western blot with 19097-1-AP (LINGO1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19097-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

19097-1-PBS targets LINGO1 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen LINGO1 fusion protein Ag13553 相同性解析による交差性が予測される生物種
Full Name leucine rich repeat and Ig domain containing 1
Calculated molecular weight 70 kDa
Observed molecular weight 83 kDa
GenBank accession numberBC011057
Gene symbol LINGO1
Gene ID (NCBI) 84894
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

LINGO-1 is a transmembrane receptor that contains 12 leucine-rich repeats and an immunoglobulin domain. It is expressed primarily in the central nervous system. LINGO-1 binds Nogo-66 receptor (NgR) and p75 and that is a functional component of the NgR/p75 signaling complex (PMID: 14966521). This protein has a calculated molecular weight of 70 kDa and migrates at higher molecular weight due to glycosylation (PMID: 21872576; 25257685; 18326721).