LOXL2 Monoclonal antibody, PBS Only
LOXL2 Monoclonal Antibody for WB, IF, IHC, Indirect ELISA
Host / Isotype
Mouse / IgG2a
Reactivity
Human, rat
Applications
WB, IF, IHC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1H7F1
Cat no : 67139-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
67139-1-PBS targets LOXL2 in WB, IF, IHC, Indirect ELISA applications and shows reactivity with Human, rat samples.
Tested Reactivity | Human, rat |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Immunogen | LOXL2 fusion protein Ag28566 相同性解析による交差性が予測される生物種 |
Full Name | lysyl oxidase-like 2 |
Calculated molecular weight | 774 aa, 87 kDa |
Observed molecular weight | 100 kDa |
GenBank accession number | BC000594 |
Gene symbol | LOXL2 |
Gene ID (NCBI) | 4017 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
LOXL2, also named as WS9-14, belongs to an amine oxidase family whose members have been implicated in crosslink formation in stromal collagens and elastin, cell motility, and tumor development and progression. LOXL2 activity might be a crucial modulator of Snail, providing an additional control mechanism of EMT and tumor progression. Increased LOXL2 expression in colon and esophageal cancer may contribute to tumor progression. We detected a band about 100 kd which is a secretory mature LOXL2 protein modified by glycosylation (PMID: 24014025).