MAD2L2 Monoclonal antibody, PBS Only
MAD2L2 Monoclonal Antibody for Indirect ELISA, IHC, WB
Host / Isotype
Mouse / IgG2b
Reactivity
rat, mouse, human
Applications
Indirect ELISA, IHC, WB
Conjugate
Unconjugated
CloneNo.
2A4C2
Cat no : 67100-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
67100-1-PBS targets MAD2L2 in Indirect ELISA, IHC, WB applications and shows reactivity with rat, mouse, human samples.
Tested Reactivity | rat, mouse, human |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Immunogen | MAD2L2 fusion protein Ag28233 相同性解析による交差性が予測される生物種 |
Full Name | MAD2 mitotic arrest deficient-like 2 (yeast) |
Calculated molecular weight | 211 aa, 24 kDa |
Observed molecular weight | 24 kDa |
GenBank accession number | BC015244 |
Gene symbol | MAD2L2 |
Gene ID (NCBI) | 10459 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
MAD family, together with BUB and Mps1,Cdc20k, play roles in the mitotic spindle checkpoint. MAD2L2 is one of the MAD family. It can mediate the second polymerase switching in translation DNA synthesis by mediating the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1. Through regulation of the JNK-mediate phosphorylation and activation of the transcriptional activator ELK1, MAD2L2 involves in cellular response to DNA damage. Also it has role in the progression of cell cycle and peithelial-mesenchymal transdifferentiation.