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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

TAB2 Recombinant antibody

TAB2 Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

230118G2

Cat no : 82948-1-RR

Synonyms

MAP3K7IP2, TAB-2, TAB 2, Mitogen-activated protein kinase kinase kinase 7-interacting protein 2, KIAA0733

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using MAP3K7IP2 Recombinant antibody (82948-1-RR)

    WB analysis using 82948-1-RR

    Various lysates were subjected to SDS PAGE followed by western blot with 82948-1-RR (MAP3K7IP2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours.

  • Affinity and Kinetic Characterization of 82948-1-RR

    Affinity and Kinetic Characterization of 82948-1-RR

    Biolayer interferometry (BLl) kinetic assays of 82948-1-RR against Human TAB2 were performed. The affinity constant is 0.107 nM.

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Tested Applications

Positive WB detected inHepG2 cells, HEK-293T cells, L02 cells, Raji cells, RAW 264.7 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

82948-1-RR targets TAB2 in WB, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen TAB2 fusion protein Ag5742 相同性解析による交差性が予測される生物種
Full Name mitogen-activated protein kinase kinase kinase 7 interacting protein 2
Calculated molecular weight 76 kDa
Observed molecular weight77 kDa
GenBank accession numberBC035910
Gene symbol MAP3K7IP2
Gene ID (NCBI) 23118
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Tab2 has a role in the inflammatory signal transduction pathway and is involved in the reversal of NCoR-dependent and NFkB- or APP-mediated gene repression and androgen antagonist response. Besides, it is identified as a cofactor for ERBB4 to assemble NCoR corepressor complex in response to neuregulin [PMID:16469706]. It also functions as an adaptor that links TAK1 and TRAF6 in response to interleukin-1β (IL-1β) or tumour necrosis factor-α (TNF-α), and thereby mediates TAK1 activation [PMID:11460167].

Protocols

Product Specific Protocols
WB protocol for TAB2 antibody 82948-1-RRDownload protocol
Standard Protocols
Click here to view our Standard Protocols