Validation Data Gallery
Tested Applications
This antibody is not recommended for immunocytofluorescent assays.
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
67733-1-PBS targets METTL3 in WB, IHC, IF-P, FC (Intra), Indirect ELISA applications and shows reactivity with Human, mouse samples.
Tested Reactivity | Human, mouse |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | METTL3 fusion protein Ag7110 相同性解析による交差性が予測される生物種 |
Full Name | methyltransferase like 3 |
Calculated molecular weight | 64 kDa |
Observed molecular weight | 65-70 kDa |
GenBank accession number | BC001650 |
Gene Symbol | METTL3 |
Gene ID (NCBI) | 56339 |
RRID | AB_2918502 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
UNIPROT ID | Q86U44 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
METTL3 is a key S-adenosyl-L-methionine-binding subunit, which is component of a complex multicomponent enzyme that catalyzes the methylation of internal adenosine residues in eukaryotic mRNA, forming N6-methyladenosine. It contains 2 putative nuclear localization signals and 2 consensus methylation motifs. The calculated molecular weight of METTL3 is 64 kDa, but modified METTL3 is about 65-70 kDa.