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METTL7A Monoclonal antibody

METTL7A Monoclonal Antibody for WB, IHC, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat, rabbit

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

CloneNo.

1A9B4

Cat no : 67905-1-Ig

Synonyms

N6-adenosine-methyltransferase TMT1A, Methyltransferase-like protein 7A, methyltransferase like 7A, EC:2.1.1.9, EC:2.1.1.348


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Tested Applications

Positive WB detected inrat liver tissue, LNCaP cells, mouse lung tissue, HepG2 cells, K-562 cells, mouse liver tissue, rabbit liver tissue
Positive IHC detected inhuman thyroid cancer tissue, human liver cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
Immunohistochemistry (IHC)IHC : 1:500-1:2000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

67905-1-Ig targets METTL7A in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat, rabbit samples.

Tested Reactivity human, mouse, rat, rabbit
Cited Reactivityhuman
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen METTL7A fusion protein Ag29986 相同性解析による交差性が予測される生物種
Full Name methyltransferase like 7A
Calculated molecular weight 28 kDa
Observed molecular weight 28 kDa
GenBank accession numberBC008180
Gene symbol METTL7A
Gene ID (NCBI) 25840
RRIDAB_2918661
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

methyltransferase like 7A (METTL7A) is a 244 amino acid protein which belongs to the methyltransferase super family. Methyltransferase can transfer a methyl group from a donor to an acceptor. Methylation may be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.

Protocols

Product Specific Protocols
WB protocol for METTL7A antibody 67905-1-IgDownload protocol
IHC protocol for METTL7A antibody 67905-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Int J Oral Sci

METTL7A-mediated m6A modification of corin reverses bisphosphonates-impaired osteogenic differentiation of orofacial BMSCs

Authors - Yizhou Jin
  • KD Validated