Validation Data Gallery
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Tested Applications
Positive WB detected in | HeLa cells, MCF-7 cells |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:500-1:1000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
23202-1-AP targets MORC2 in WB, ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | MORC2 fusion protein Ag19605 相同性解析による交差性が予測される生物種 |
Full Name | MORC family CW-type zinc finger 2 |
Calculated molecular weight | 970 aa, 111 kDa |
Observed molecular weight | 118 kDa |
GenBank accession number | BC136782 |
Gene Symbol | MORC2 |
Gene ID (NCBI) | 22880 |
RRID | AB_3669412 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q9Y6X9 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
MORC2 is essential for epigenetic silencing by the HUSH (human silencing hub) complex. It can be recruited by HUSH to target site in heterochromatin. MORC2 also recruits histone deacetylases, such as HDAC4, to promoter regions, causing local histone H3 deacetylation and transcriptional repression of genes.
Protocols
Product Specific Protocols | |
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WB protocol for MORC2 antibody 23202-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |