Validation Data Gallery
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Tested Applications
| Positive IHC detected in | human lung cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:20-1:200 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| KD/KO | See 1 publications below |
| IHC | See 2 publications below |
Product Information
14650-1-AP targets MPP3 in IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
| Tested Reactivity | human, mouse, rat |
| Cited Reactivity | mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | MPP3 fusion protein Ag6246 相同性解析による交差性が予測される生物種 |
| Full Name | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| Calculated molecular weight | 66 kDa |
| GenBank accession number | BC056865 |
| Gene Symbol | MPP3 |
| Gene ID (NCBI) | 4356 |
| RRID | AB_10949194 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q13368 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
MPP3, also named as DLG3, belongs to the MAGUK family which interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. MPP3 plays an important role in signal transduction.
Protocols
| Product Specific Protocols | |
|---|---|
| IHC protocol for MPP3 antibody 14650-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
J Neurosci PALS1 is essential for retinal pigment epithelium structure and neural retina stratification. | ||
J Neurosci MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex.
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