MYB/c-Myb Monoclonal antibody, PBS Only
MYB/c-Myb Monoclonal Antibody for WB, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse, pig
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2A12C2
Cat no : 60550-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
60550-1-PBS targets MYB/c-Myb in WB, Indirect ELISA applications and shows reactivity with human, mouse, pig samples.
| Tested Reactivity | human, mouse, pig |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | MYB/c-Myb fusion protein Ag34185 相同性解析による交差性が予測される生物種 |
| Full Name | v-myb myeloblastosis viral oncogene homolog (avian) |
| Calculated molecular weight | 640 aa, 72 kDa |
| Observed molecular weight | 40-50 kDa, 72-80 kDa |
| GenBank accession number | BC064955 |
| Gene symbol | c-Myb |
| Gene ID (NCBI) | 4602 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
The MYB protein is a transcription factor that plays a key role in regulating the proliferation/differentiation of progenitor cells in bone marrow, colonic crypts, and neurogenic niches [PMID:18574464]. It is involved in the regulation of epithelial-to-mesenchymal transition (EMT) and invasion in neuroblastoma, colon carcinoma, and embryonic kidney cells through the upregulation of the transcription repressor Slug [PMID:20622260]. It also a DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3', and plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. MYB exists some isoforms with MV 85, 75, 72, 68, 63 and 40 kDa.
