MYL3 Monoclonal antibody, PBS Only (Capture)
MYL3 Monoclonal Antibody for WB, IHC, Cytometric bead array, Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human, mouse, rat, pig
Applications
WB, IHC, Cytometric bead array, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
2E4B2
Cat no : 66286-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
66286-1-PBS targets MYL3 as part of a matched antibody pair:
MP50642-3: 66286-1-PBS capture and 66286-5-PBS detection (validated in Cytometric bead array)
Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
Tested Reactivity | human, mouse, rat, pig |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Immunogen | MYL3 fusion protein Ag24535 相同性解析による交差性が予測される生物種 |
Full Name | myosin, light chain 3, alkali; ventricular, skeletal, slow |
Calculated molecular weight | 22 kDa |
Observed molecular weight | 22-25 kDa |
GenBank accession number | BC009790 |
Gene symbol | MYL3 |
Gene ID (NCBI) | 4634 |
RRID | AB_2881669 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein G purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
MYL3, also named as MLC1v, is an essential light chain of myosin that is associated with muscle contraction. It is expressed in ventricular and slow skeletal muscle. MYL3 may serve as a target for caspase-3 in dying cardiomyocytes. Mutations of MYL3 gene cause hypertrophic cardiomyopathy. MYL3 has been identified as potential serum biomarker for drug induced myotoxicity. Great increase in MYL3 serum concentration has been observed in rats with cardiac and skeletal muscle injury. (PMID:21685905)