MultiProTM-5CFLX Anti-Human CXCL8/IL-8 (Polyclonal)
CXCL8/IL-8 Polyclonal Antibody for
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
Conjugate
5CFLX Fluorescent Dye
Cat no : G17038-1-5C
Synonyms
Validation Data Gallery
Tested Applications
Positive Single Cell (Intra) detected in | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product |
Recommended dilution
Application | Dilution |
---|---|
SINGLE CELL (INTRA) | SINGLE CELL (INTRA) : <0.5ug/test |
Sample-dependent, check data in validation data gallery |
Product Information
G17038-1-5C targets CXCL8/IL-8 in applications and shows reactivity with Human samples.
Tested Reactivity | Human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | CXCL8/IL-8 fusion protein Ag10552 相同性解析による交差性が予測される生物種 |
Full Name | interleukin 8 |
Calculated molecular weight | 99 aa, 11 kDa |
GenBank accession number | BC013615 |
Gene symbol | IL8 |
Gene ID (NCBI) | 3576 |
Conjugate | 5CFLX Fluorescent Dye |
Form | Liquid |
Purification Method | |
Storage Buffer | PBS with 1mM EDTA and 0.09% sodium azide |
Storage Conditions | 2-8°C |
Background Information
Interleukin 8 (IL-8), also known as CXCL8, which is a member of the CXC chemokine family. This chemokine is secreted by a variety of cell types including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, and various tumor cell lines in response to inflammatory stimuli. IL-8 has two primary functions. It induces chemotaxis in target cells, primarily neutrophils but also other granulocytes, causing them to migrate toward the site of infection. IL-8 also induces phagocytosis once they have arrived. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. IL-8 is also known to be a potent promoter of angiogenesis. IL-8 has been associated with tumor angiogenesis, metastasis, and poor prognosis in breast cancer. IL-8 may present a novel therapeutic target for estrogen driven breast carcinogenesis and tumor progression.