neuromedin B Polyclonal antibody
neuromedin B Polyclonal Antibody for IHC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse and More (2)
Applications
WB, IHC, ELISA
Conjugate
Unconjugated
Cat no : 10888-1-AP
Synonyms
Validation Data Gallery
Tested Applications
| Positive IHC detected in | mouse brain tissue, human brain tissue, human breast cancer tissue, human skin tissue, human stomach tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
| Application | Dilution |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Published Applications
| WB | See 1 publications below |
| IHC | See 2 publications below |
Product Information
10888-1-AP targets neuromedin B in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, monkey, chimpanzee |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | neuromedin B fusion protein Ag0842 相同性解析による交差性が予測される生物種 |
| Full Name | neuromedin B |
| Calculated molecular weight | 16 kDa |
| GenBank accession number | BC007407 |
| Gene symbol | NMB |
| Gene ID (NCBI) | 4828 |
| RRID | AB_10895967 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Neuromedin B (NMB) is a bombesin-like peptide, which inhibits food intake and modulates stress-related behaviour. It exerts its function via NMB receptor (NMB-R). NMB is encoded in a 76-amino acid precursor. The mature NMB was reported to be a 10-amino-acid peptide, giving two bands of 1.2 kDa and 1.5 kDa in western blotting. NMB is expressed in brain, gastrointestinal tract, pancreas, adrenals, and adipose tissue. It regulates exocrine and endocrine secretions, cell growth, body temperature and blood pressure and glucose level in vivo.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for neuromedin B antibody 10888-1-AP | Download protocol |
| IHC protocol for neuromedin B antibody 10888-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Brain Struct Funct The von Economo neurons in frontoinsular and anterior cingulate cortex in great apes and humans. | ||
Cancer Lett Neuromedin B receptor antagonist suppresses tumor angiogenesis and tumor growth in vitro and in vivo. | ||
