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- KD/KO Validated
NPRL2 Polyclonal antibody, PBS Only
NPRL2 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
WB, IHC, IP, Indirect ELISA
Conjugate
Unconjugated
Cat no : 10157-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
10157-1-PBS targets NPRL2 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Reactivity | human, mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | NPRL2 fusion protein Ag0210 相同性解析による交差性が予測される生物種 |
Full Name | tumor suppressor candidate 4 |
Calculated molecular weight | 44 kDa |
Observed molecular weight | 44-50 kDa |
GenBank accession number | BC002791 |
Gene symbol | TUSC4 |
Gene ID (NCBI) | 10641 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
NPRL2 (NPR2 Like, GATOR1 Complex Subunit) is a Protein Coding gene associated with Epilepsy, Familial Focal. As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. Homologous to yeast nitrogen permease (candidate tumor suppressor) (NM_006545, BC021984) gene encodes a protein of molecular mass of 50 kDa. Data by using overlapping and nested homozygous deletions methods indicate that this protein might be a tumor suppressor involved in the development of lung cancers.