NSUN6 Monoclonal antibody
NSUN6 Monoclonal Antibody for WB, ELISA
Host / Isotype
Mouse / IgG1
Reactivity
Human, pig
Applications
WB, ELISA
Conjugate
Unconjugated
CloneNo.
1H1H8
Cat no : 68614-1-Ig
Synonyms
Validation Data Gallery
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Tested Applications
| Positive WB detected in | U2OS cells, HeLa cells, HEK-293 cells, HepG2 cells, K-562 cells, Mo7e cells, Ramos cells, Raji cells, pig liver tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:5000-1:50000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
68614-1-Ig targets NSUN6 in WB, ELISA applications and shows reactivity with Human, pig samples.
| Tested Reactivity | Human, pig |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | NSUN6 fusion protein Ag11084 相同性解析による交差性が予測される生物種 |
| Full Name | NOL1/NOP2/Sun domain family, member 6 |
| Calculated molecular weight | 469 aa, 52 kDa |
| Observed molecular weight | 50-52 kDa |
| GenBank accession number | BC035778 |
| Gene symbol | NSUN6 |
| Gene ID (NCBI) | 221078 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
NSUN6 is an RNA methyltransferase that catalyzes the methylation at position cytosine C72 in some tRNAs. NSUN6 has been reported to localize to the cytoplasm and largely colocalize with the Golgi apparatus and pericentriolar matrix, indicating that NSUN6 modifies tRNAs in a late step in their biogenesis. NSUN6 may also play a major role in bone metastasis and could be a valuable therapeutic target for bone metastasis.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for NSUN6 antibody 68614-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
