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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

NeutraKine®FGF basic Monoclonal antibody

NeutraKine®FGF basic Monoclonal Antibody for ELISA, Neutralization

Host / Isotype

Mouse / IgG1

Reactivity

Human and More (1)

Applications

ELISA, Neutralization, Cell treatment

Conjugate

Unconjugated

CloneNo.

3C9C3

Cat no : 69024-1-Ig

Synonyms

Basic fibroblast growth factor, BFGF, FGF basic, FGF2, FGFB, FGFbasic, HBGF 2

Validation Data Gallery

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  • Neutralization experiment of NeutraKine®FGF basic using NeutraKine®FGF basic Monoclonal antibody (69024-1-Ig)

    Neutralization experiment of NeutraKine®FGF basic using 69024-1-Ig

    Recombinant human FGF Basic (Cat.NO. HZ-1285) stimulates the proliferation of BALB/3T3 cells (mouse fibroblast cell) at low FBS condition in a dose-dependent manner (blue curve, refer to bottom X-left Y axis). The activity of human FGF Basic (0.1 ng/mL HZ-1285) is neutralized by mouse anti-human FGF Basic monoclonal antibody 69024-1-Ig at serial dose (red curve, refer to top X-right Y axis). The ND50 is typically 1-10 μg/mL. Mouse IgG1 Isotype Control monoclonal antibody 66360-1-Ig was served as control (green curve, refer to top X-right Y axis).

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Neutralization

Product Information

69024-1-Ig targets NeutraKine®FGF basic in ELISA, Neutralization, Cell treatment applications and shows reactivity with Human samples.

Tested Reactivity Human
Cited Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen human HumankineFGF basic protein HZ-1285 相同性解析による交差性が予測される生物種
Full Name fibroblast growth factor 2 (basic)
Gene symbol FGF2
Gene ID (NCBI) 2247
RRIDAB_2918844
Conjugate Unconjugated
Form Lyophilized Powder
Purification MethodProtein G purification
Storage Buffer Sterile PBS.
Endotoxin<0.1 EU/μg
ReconstitutionThis product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.
Stability and StorageLyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.

Background Information

Fibroblast growth factor-2 (FGF-2), also referred to as basic FGF, belongs to a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in at least five different isoforms with distinct properties.

This antibody is used to neutralize the bioactivity of FGFbasic-TS.

Publications

SpeciesApplicationTitle
humanCell treatment

Int Immunopharmacol

Cancer-associated fibroblasts promote gastric cancer cell proliferation by paracrine FGF2-driven ribosome biogenesis

Authors - Dandan Li
View Article