SLCO1B3/OATP1B3 Polyclonal antibody
SLCO1B3/OATP1B3 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, ELISA
Conjugate
Unconjugated
Cat no : 22815-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | HeLa cells, L02 cells, human placenta tissue |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:500-1:1000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
22815-1-AP targets SLCO1B3/OATP1B3 in WB, ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | SLCO1B3/OATP1B3 fusion protein Ag18940 相同性解析による交差性が予測される生物種 |
Full Name | solute carrier organic anion transporter family, member 1B3 |
Calculated molecular weight | 702 aa, 77 kDa |
Observed molecular weight | 70-75 kDa |
GenBank accession number | BC105597 |
Gene symbol | SLCO1B3 |
Gene ID (NCBI) | 28234 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
SLCO1B3, also known as OATP8 or OATP1B3, is a member of Organic Anion Transporting Polypeptides (OATPs) which are sodium-independent organic anion transporters mediating the uptake of a wide range of structurally diverse endogenous and exogenous compounds including bile acids, hormone conjugates, peptides, toxins, as well as a multitude of therapeutic drugs. SLCO1B3 is specifically expressed in liver under normal condition, while its expression has also been observed in cancer tissues like colon, prostate and pancreas. SLCO1B3 is a glycosylated protein and can be detected in the non-glycosylated form at 70-75 kDa(PMID: 21278621).
Protocols
Product Specific Protocols | |
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WB protocol for SLCO1B3/OATP1B3 antibody 22815-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |