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Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
66276-1-PBS targets OTUD7B in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | OTUD7B fusion protein Ag10513 相同性解析による交差性が予測される生物種 |
| Full Name | OTU domain containing 7B |
| Calculated molecular weight | 427aa,48 kDa; 843aa,93 kDa |
| Observed molecular weight | 92 kDa |
| GenBank accession number | BC020622 |
| Gene Symbol | OTUD7B |
| Gene ID (NCBI) | 56957 |
| RRID | AB_2881659 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q6GQQ9 |
| Storage Buffer | PBS only , pH 7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
OUTD7B is a member of the A20 family of the deubiquitinating cysteine proteases, which has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. It plays a key role in the negative feedback regulation of NF-κB signaling in response to multiple stimuli and has been described as central gatekeeper in inflammation and immunity.