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Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
66295-1-PBS targets P-cadherin in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | P-cadherin fusion protein Ag4758 相同性解析による交差性が予測される生物種 |
| Full Name | cadherin 3, type 1, P-cadherin (placental) |
| Calculated molecular weight | 829 aa, 91 kDa |
| Observed molecular weight | 120 kDa |
| GenBank accession number | BC041846 |
| Gene Symbol | P-cadherin |
| Gene ID (NCBI) | 1001 |
| RRID | AB_2881678 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | P22223 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. P-cadherin (placental cadherin), also known as CDH3 (cadherin 3), is a classical member of the cadherin superfamily which also include E-, N-, R-, and B-cadherins. Aberrant expression of P-cadherin has been reported in many cancers, including breast, gastric, endometrial, ovarian, and prostate cancer.