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PABPC1,PABP Monoclonal antibody, PBS Only

PABPC1,PABP Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 66809-1-PBS
Clone No.3D8B5

Host / Isotype

Mouse / IgG1

Reactivity

Human, rat, mouse

Applications

WB, IHC, IF/ICC, Indirect ELISA

PAB1, PABP, PABP 1, PABP1, PABPC1, PABPC1,PABP, PABPC2, PABPL1, Poly(A) binding protein 1

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


ご購入について

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国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

66809-1-PBS targets PABPC1,PABP in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with Human, rat, mouse samples.

Tested Reactivity Human, rat, mouse
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen PABPC1,PABP fusion protein Ag27860 相同性解析による交差性が予測される生物種
Full Name poly(A) binding protein, cytoplasmic 1
Calculated molecular weight 71 kDa
Observed molecular weight 71 kDa
GenBank accession numberBC015958
Gene Symbol PABPC1
Gene ID (NCBI) 26986
RRIDAB_2882152
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP11940
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

The poly(A)-binding protein (PABP), which is found complexed to the 3-prime poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation [PMID: 21989405]. Polyadenylate-binding protein 1 (PABPC1) is a cytoplasmic-nuclear shuttling protein important for protein translation initiation, and both RNA processing and stability. In the cytoplasm, PABPC1 binds to the 3' poly(A) tail of eukaryotic mRNAs through its RNA-recognition motifs (RRM) and interacts with the N-terminus of eIF4G, part of the eIF4F complex associated with the 5' cap structure [PMID:20009508, 17381337].

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