Mouse PD-L1/B7-H1 Recombinant antibody, PBS Only
PD-L1/B7-H1 Recombinant Antibody for WB, IHC, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
mouse
Applications
WB, IHC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
240993C9
Cat no : 83906-6-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
The immunogen of 83906-6-PBS is PD-L1/B7-H1 Fusion Protein expressed in E. coli.
| Tested Reactivity | mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen | Fusion Protein 相同性解析による交差性が予測される生物種 |
| Full Name | CD274 antigen |
| Calculated molecular weight | 33 kDa |
| Observed molecular weight | 45 kDa |
| GenBank accession number | NM_021893.3 |
| Gene symbol | PD-L1 |
| Gene ID (NCBI) | 60533 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
Background Information
Programmed cell death ligand 1 (PD-L1, CD274, or B7-H1), is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. PD-L1 is suggested as a negative regulator of T and B cell, and plays important role in mediating tolerance of lymphocytes to self-antigens. It is also involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PD-1-independent manner.
