Validation Data Gallery
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Tested Applications
| Positive WB detected in | Y79 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:200-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
55183-1-AP targets PDE6C in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide 相同性解析による交差性が予測される生物種 |
| Full Name | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| Calculated molecular weight | 99 kDa |
| Observed molecular weight | 52 kDa, 99 kDa |
| GenBank accession number | NM_006204 |
| Gene Symbol | PDE6C |
| Gene ID (NCBI) | 5146 |
| RRID | AB_10837359 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P51160 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
Background Information
PDE6C, also named as PDEA2, belongs to the cyclic nucleotide phosphodiesterase family. It catalyze the reaction: Guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. Defects in PDE6C are the cause of cone dystrophy type 4 (COD4). Mutations in the PDE6C gene encoding the catalytic subunit of the cone photoreceptor phosphodiesterase as a cause of autosomal recessive achromatopsia.(PMID:19887631) This antibody is specific to PDE6C.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for PDE6C antibody 55183-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |