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PDE6C Polyclonal antibody

PDE6C Polyclonal Antibody for WB, ELISA
Cat No. 55183-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

cGMP phosphodiesterase 6C, PDE6C, PDEA2

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -


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保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Positive WB detected inY79 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

55183-1-AP targets PDE6C in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide 相同性解析による交差性が予測される生物種
Full Name phosphodiesterase 6C, cGMP-specific, cone, alpha prime
Calculated molecular weight 99 kDa
Observed molecular weight 52 kDa, 99 kDa
GenBank accession numberNM_006204
Gene Symbol PDE6C
Gene ID (NCBI) 5146
RRIDAB_10837359
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP51160
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage.

Background Information

PDE6C, also named as PDEA2, belongs to the cyclic nucleotide phosphodiesterase family. It catalyze the reaction: Guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. Defects in PDE6C are the cause of cone dystrophy type 4 (COD4). Mutations in the PDE6C gene encoding the catalytic subunit of the cone photoreceptor phosphodiesterase as a cause of autosomal recessive achromatopsia.(PMID:19887631) This antibody is specific to PDE6C.

Protocols

Product Specific Protocols
WB protocol for PDE6C antibody 55183-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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