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  • KD/KO Validated

RKIP Polyclonal antibody

RKIP Polyclonal Antibody for WB, IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Cat no : 10575-1-AP

Synonyms

PEBP1, PEBP 1, PEBP, PBP, Neuropolypeptide h3


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Tested Applications

Positive WB detected inmouse brain tissue, mouse liver tissue, mouse testis tissue
Positive IHC detected inhuman colon cancer tissue, human stomach cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

10575-1-AP targets RKIP in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen RKIP fusion protein Ag0864 相同性解析による交差性が予測される生物種
Full Name phosphatidylethanolamine binding protein 1
Calculated molecular weight 21 kDa
Observed molecular weight 23 kDa
GenBank accession numberBC008714
Gene symbol PEBP1
Gene ID (NCBI) 5037
RRIDAB_2299521
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Raf kinase inhibitor protein (RKIP), also termed phosphatidylethanolamine binding protein PEBP1, was initially identified as a potent inhibitor of Raf-1/MEK/ERK, NF-kB, and G-protein-coupled receptor signaling pathways. Later RKIP has been further identified as a metastasis suppressor and its loss of expression has been reported in various cancers. Its expression has been proposed as a prognostic marker for patients diagnosed with the above cancers.

Protocols

Product Specific Protocols
WB protocol for RKIP antibody 10575-1-APDownload protocol
IHC protocol for RKIP antibody 10575-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIHC

FASEB J

Menstrual fluid factors facilitate tissue repair: identification and functional action in endometrial and skin repair.

Authors - Jemma Evans
humanIHC

Anticancer Res

Differential Protein Expression of Lymph Node Metastases of Papillary Thyroid Carcinoma Harboring the BRAF Mutation.

Authors - Park Won Seo WS
mouseWB

J Ethnopharmacol

AR/RKIP pathway mediates the inhibitory effects of icariin on renal fibrosis and endothelial-to-mesenchymal transition in type 2 diabetic nephropathy

Authors - Wenhui Yao
  • KD Validated
humanIHC

Medicine (Baltimore)

Prognostic significance of RKIP, TGM2, and CMTM4 expression in oral squamous cell carcinoma

Authors - Tianyu Luo