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- KD/KO Validated
PELI1 Polyclonal antibody, PBS Only
PELI1 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, IHC, IP, Indirect ELISA
Conjugate
Unconjugated
Cat no : 12053-1-PBS
Synonyms
Validation Data Gallery
Tested Applications
Recommended dilution
Application | Dilution |
---|---|
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
Product Information
12053-1-PBS targets PELI1 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | PELI1 fusion protein Ag2683 相同性解析による交差性が予測される生物種 |
Full Name | pellino homolog 1 (Drosophila) |
Calculated molecular weight | 418 aa, 46 kDa |
Observed molecular weight | 46-53 kDa |
GenBank accession number | BC011419 |
Gene symbol | PELI1 |
Gene ID (NCBI) | 57162 |
RRID | AB_2161180 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. |
Background Information
PELI1 encodes pellino-1, an E3 ubiquitin-protein ligase pellino homolog. E3 ubiquitin ligase functions by catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Pellino-1 is involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Pellino-1 can mediate 'Lys-63'-linked polyubiquitination of IRAK1 allowing subsequent NF-kappa-B activation thus playing a role in cellular inflammation. This antibody may cross react with Pellino-3.