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Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
15481-1-PBS targets PEX11A in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | PEX11A fusion protein Ag7797 相同性解析による交差性が予測される生物種 |
| Full Name | peroxisomal biogenesis factor 11 alpha |
| Calculated molecular weight | 28 kDa |
| Observed molecular weight | 28 kDa |
| GenBank accession number | BC009697 |
| Gene Symbol | PEX11A |
| Gene ID (NCBI) | 8800 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | O75192 |
| Storage Buffer | PBS only , pH 7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
Peroxisomes are ubiquitous organelles bound by a single membrane. Peroxisomal biogenesis factor 11 alpha (PEX11A) is one of PEX11 gene family members involved in peroxisome elongation. PEX11A is highly expressed in the kidney and liver (PMID: 25113963). PEX11A deficiency will impaire peroxisome elongation, leading to the reduction of functional peroxisome, eventually leading to the reduction of fatty acid oxidation capacity and the formation of steatosis (PMID: 23169785; PMID: 25113963)