PGLYRP1 Polyclonal antibody
PGLYRP1 Polyclonal Antibody for WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat
Applications
WB, ELISA
Conjugate
Unconjugated
Cat no : 18046-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | rat brain tissue |
Recommended dilution
Application | Dilution |
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Western Blot (WB) | WB : 1:500-1:1000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
18046-1-AP targets PGLYRP1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | PGLYRP1 fusion protein Ag12690 相同性解析による交差性が予測される生物種 |
Full Name | peptidoglycan recognition protein 1 |
Calculated molecular weight | 196 aa, 22 kDa |
Observed molecular weight | 25 kDa |
GenBank accession number | BC101845 |
Gene symbol | PGLYRP1 |
Gene ID (NCBI) | 8993 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
Peptidoglycan recognition protein 1 (PGLYRP1, also known as PGRP-S) belongs to a family of evolutionary conserved innate immunity proteins, which in mammals also include PGLYRP2, PGLYRP3, and PGLYRP4 (PMID: 17275309; 20418257). PGLYRP1 is highly expressed in polymorphonuclear leukocytes and to a lower extent in many non-immune cells (PMID: 20418257). It recognizes bacterial peptidoglycan and functions in antibacterial immunity and inflammation (PMID: 20418257). PGLYRP1 has been identified as a ligand for TREM-1 (PMID: 25595774).
Protocols
Product Specific Protocols | |
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WB protocol for PGLYRP1 antibody 18046-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |