Validation Data Gallery
Tested Applications
Recommended dilution
| Application | Dilution |
|---|---|
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Product Information
67201-1-PBS targets PITX2 in Indirect ELISA, WB applications and shows reactivity with rat, mouse, human samples.
| Tested Reactivity | rat, mouse, human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Immunogen | PITX2 fusion protein Ag27924 相同性解析による交差性が予測される生物種 |
| Full Name | paired-like homeodomain 2 |
| Calculated molecular weight | 36 kDa |
| Observed molecular weight | 30 kDa |
| GenBank accession number | BC013998 |
| Gene Symbol | PITX2 |
| Gene ID (NCBI) | 5308 |
| RRID | AB_2882494 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q99697 |
| Storage Buffer | PBS only , pH 7.3 |
| Storage Conditions | Store at -80°C. |
Background Information
PITX2 belongs to the bicoid class of homeodomain transcription factors, which play essential roles in embryonic development. Various PITX2 isoforms are involved in a wide variety of developmental programs, including left-right signaling. It controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, PITX2 is involved in the expansion of muscle progenitors. In addition, it may play a role in the proper localization of asymmetric organs such as the heart and stomach. PITX2 can be bound by some other proteins, and are part of a much larger atrial transcriptional complex. This antibody specifically recognizes isoform PTX2C.