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Species Reactivity

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  • Featured Product
  • KD/KO Validated

PLAGL2 Polyclonal antibody, PBS Only

PLAGL2 Polyclonal Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

Cat no : 11540-1-PBS

Synonyms

Validation Data Gallery

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  • Western Blot (WB) analysis of various lysates using PLAGL2 Polyclonal antibody (11540-1-AP)

    WB analysis using 11540-1-AP (same clone as 11540-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11540-1-AP (PLAGL2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11540-1-PBS in a different storage buffer formulation.

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Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

11540-1-PBS targets PLAGL2 in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen PLAGL2 fusion protein Ag2137 相同性解析による交差性が予測される生物種
Full Name pleiomorphic adenoma gene-like 2
Calculated molecular weight 496 aa, 55 kDa
Observed molecular weight 50-55 kDa, 70 kDa
GenBank accession numberBC023655
Gene symbol PLAGL2
Gene ID (NCBI) 5326
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

PLAGL2, also named KIAA0198, belongs to the krueppel C2H2-type zinc-finger protein family. It shows weak transcriptional activatory activity. PLAGL2, a proto-oncogene, is implicated in a variety of cancers including acute myeloid leukemia (AML), malignant glioma, colon cancer, and lung adenocarcinoma. PLAGL2 can function as a tumor suppressor by initiating cell cycle arrest and apoptosis. The calculated molecular weight of PLAGL2 is 55 kDa, but the SUMO1-modifIed form is 68 kDa (PMID: 30535429).