• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
×

Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

Validation Data Gallery

Filter:
  • Western Blot (WB) analysis of HeLa cells using POT1 Polyclonal antibody (10581-1-AP)

    WB analysis of HeLa using 10581-1-AP (same clone as 10581-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 10581-1-AP (POT1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10581-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of PC-3 cells using POT1 Polyclonal antibody (10581-1-AP)

    WB analysis of PC-3 using 10581-1-AP (same clone as 10581-1-PBS)

    PC-3 cells were subjected to SDS PAGE followed by western blot with 10581-1-AP (POT1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10581-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HeLa cells using POT1 Polyclonal antibody (10581-1-AP)

    WB analysis of HeLa using 10581-1-AP (same clone as 10581-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 10581-1-AP (POT1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10581-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HeLa cells using POT1 Polyclonal antibody (10581-1-AP)

    WB analysis of HeLa using 10581-1-AP (same clone as 10581-1-PBS)

    HeLa cells were subjected to SDS PAGE followed by western blot with 10581-1-AP (POT1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10581-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human prostate cancer tissue using POT1 Polyclonal antibody (10581-1-AP)

    IHC staining of human prostate cancer using 10581-1-AP (same clone as 10581-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer using 10581-1-AP (POT1 antibody) at dilution of 1:100 (under 25x lens). This data was developed using the same antibody clone with 10581-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human cervical cancer tissue using POT1 Polyclonal antibody (10581-1-AP)

    IHC staining of human cervical cancer using 10581-1-AP (same clone as 10581-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 10581-1-AP (POT1 Antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 10581-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human cervical cancer tissue using POT1 Polyclonal antibody (10581-1-AP)

    IHC staining of human cervical cancer using 10581-1-AP (same clone as 10581-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 10581-1-AP (POT1 Antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 10581-1-PBS in a different storage buffer formulation.

［PR］まずは試したいあなたに。トライアルサイズも特別価格 >>『PRIME BUY抗体特割キャンペーン（4/21～）』

POT1 Polyclonal antibody, PBS Only

POT1 Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 10581-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, Indirect ELISA

Synonyms

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

ご購入について

国内販売は「コスモ・バイオ株式会社」を通じて行っております。お見積り・ご注文はお近くの販売代理店へご連絡ください。

国内在庫・納期について

約2万点のプロテインテック製品をコスモバイオ社物流センター（国内）に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。

保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換／補填対応を承ります。詳細はこちらをご覧ください。

Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

10581-1-PBS targets POT1 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen POT1 fusion protein Ag0875 相同性解析による交差性が予測される生物種
Full Name POT1 protection of telomeres 1 homolog (S. pombe)
Calculated molecular weight 71 kDa
Observed molecular weight 45 kDa, 71 kDa
GenBank accession numberBC002923
Gene Symbol POT1
Gene ID (NCBI) 25913
RRIDAB_2284057
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9NUX5
Storage Buffer PBS only , pH 7.3
Storage ConditionsStore at -80°C.

Background Information

Protection of telomeres 1(POT1) is a conserved protein that binds the G-rich stand of its own telomeric repeat sequence, with a role in protecting chromosome ends. It's housekeeping gene that is required to ensure the integrity of chromosome ends in all cells. It's a component of the telomerase ribonucleoprotein(RNP) complex that is esential for the replication of chromosome termini. It consists the TRF1 compex that is involved in the regulation of telomere length by cis-inhibition of telomerase. We have discovered that POT1 exists in at least three consistently occurring forms; 90, 70 and 45kDa. The unexpected molecular weights of POT1 seem to be associated with SUMO1 and ubiquitin conjugation; the latter occurring at a double lysine residue at 289-KK-290 (.PMID: 24054699)