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Target

Host

Species Reactivity

Species Reactivity

Conjugate

Conjugate

PROCR Polyclonal antibody

PROCR Polyclonal Antibody for WB, IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

Cat no : 11391-1-AP

Synonyms

CD201, EPCR, CCD41, CCCA, bA42O4.2

Validation Data Gallery

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  • Western Blot (WB) analysis of human spleen tissue using PROCR Polyclonal antibody (11391-1-AP)

    WB analysis of human spleen using 11391-1-AP

    human spleen tissue were subjected to SDS PAGE followed by western blot with 11391-1-AP (PROCR antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

  • Immunohistochemistry (IHC) staining of human pancreas cancer tissue using PROCR Polyclonal antibody (11391-1-AP)

    IHC staining of human pancreas cancer using 11391-1-AP

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 11391-1-AP (EPCR antibody at dilution of 1:100 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human pancreas cancer tissue using PROCR Polyclonal antibody (11391-1-AP)

    IHC staining of human pancreas cancer using 11391-1-AP

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 11391-1-AP (EPCR antibody at dilution of 1:100 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human lung cancer tissue using PROCR Polyclonal antibody (11391-1-AP)

    IHC staining of human lung cancer using 11391-1-AP

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 11391-1-AP (PROCR antibody at dilution of 1:100 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human lung cancer tissue using PROCR Polyclonal antibody (11391-1-AP)

    IHC staining of human lung cancer using 11391-1-AP

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 11391-1-AP (PROCR antibody at dilution of 1:100 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human pancreas cancer tissue using PROCR Polyclonal antibody (11391-1-AP)

    IHC staining of human pancreas cancer using 11391-1-AP

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer using 11391-1-AP (EPCR antibody) at dilution of 1:50 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human lung cancer tissue using PROCR Polyclonal antibody (11391-1-AP)

    IHC staining of human lung cancer using 11391-1-AP

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 11391-1-AP (EPCR antibody at dilution of 1:100 (under 10x lens).

  • Immunohistochemistry (IHC) staining of human lung cancer tissue using PROCR Polyclonal antibody (11391-1-AP)

    IHC staining of human lung cancer using 11391-1-AP

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 11391-1-AP (EPCR antibody at dilution of 1:100 (under 40x lens).

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Tested Applications

Positive WB detected inhuman spleen tissue
Positive IHC detected inhuman pancreas cancer tissue, human lung cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

11391-1-AP targets PROCR in WB, IHC, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen PROCR fusion protein Ag1937 相同性解析による交差性が予測される生物種
Full Name protein C receptor, endothelial (EPCR)
Calculated molecular weight 238 aa, 27 kDa
Observed molecular weight 49 kDa
GenBank accession numberBC014451
Gene symbol PROCR
Gene ID (NCBI) 10544
RRIDAB_2268938
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Protein C receptor (PROCR), also known as activated protein C receptor (APC receptor), EPCR, or CD201, is a transmembrane glycoprotein. EPCR promotes the activation of protein C, which has anticoagulant and cytoprotective effects. EPCR facilitates the activation of protein C by the thrombin-thrombomodulin complex but also facilitates APC-mediated cytoprotective effects on cells that involve the activation of protease-activated receptors (PAR) 1 and 3(PMID: 27207424).

Protocols

Product Specific Protocols
WB protocol for PROCR antibody 11391-1-APDownload protocol
IHC protocol for PROCR antibody 11391-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle

Analyst

An iTRAQ based quantitative proteomic strategy to explore novel secreted proteins in metastatic hepatocellular carcinoma cell lines.

Authors - Yu Yanyan Y
View Article