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PSPC1 Recombinant antibody, PBS Only

PSPC1 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 84657-4-PBS
Clone No.242158G7

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

PSPC 1, PSP1, 242158G7

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -


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約2万点のプロテインテック製品をコスモバイオ社物流センター(国内)に在庫しています。国内在庫の有無はコスモバイオ社ホームページの「品番検索」でカタログ番号を検索して確認できます。


保証・サポートについて

テクニカルサポートまたはご購入後1年間の交換/補填対応を承ります。詳細はこちらをご覧ください。


Tested Applications

Recommended dilution

ApplicationDilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Product Information

84657-4-PBS targets PSPC1 in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen PSPC1 fusion protein Ag10136 相同性解析による交差性が予測される生物種
Full Name paraspeckle component 1
Calculated molecular weight 523 aa, 59 kDa
Observed molecular weight 66 kDa
GenBank accession numberBC014184
Gene Symbol PSPC1
Gene ID (NCBI) 55269
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ8WXF1
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

Background Information

PSPC1 (paraspeckle component 1), a known paraspeckle biomarker, is a putative transcription factor that belongs to the Drosophila behavior/human splicing (DBHS) family. PSPC1 was recently identified as a contextual determinant of tumor progression in multiple cancer types involving oncogenic reprogramming to switch proapoptotic TGF-β to prometastatic TGF-β via hijacking of Smad2/3 targeting. Upregulated PSPC1 is correlated with advanced tumor stages and poor survival of patients with breast, lung, and liver cancers. Upregulated PSPC1 potentiates expression of mesenchymal markers, EMT transcription factors (EMT-TF), cancer stem-like cell transcription factors (CSC-TF), and c-Myc-related proliferation genes, thus promoting migration, invasion, spheroid formation, tumor formation, and metastasis.

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